c. Genetic mutation in the GRE, d. zinc deficiency in a patient might disrupt normal association of glucocorticoids with their DNA binding sites and be cause for concern
Genetic mutations in the GRE (glucocorticoid receptor elements) are an important factor in determining the effectiveness of glucocorticoid hormone therapy.
If a patient is deficient in zinc, this can interfere with the normal binding of glucocorticoids to their DNA binding sites, which can be a cause for concern.
In order to ensure that the treatment is effective, patients must have adequate zinc levels in order for the glucocorticoids to be properly bound to their respective DNA binding sites. By doing so, the effectiveness of the treatment is increased and the risk of side effects is minimized.
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Why are plants unable to grow at the bottom of lakes the water is colder at the bottom sunlight does not reach the bottom?
Because the water is so deep. There are no rooted plants to be found at the bottom of lakes because sunlight cannot penetrate that far.
Lakes obtain their water supply from three different sources: precipitation; rivers and streams; and underground water.
The size of lakes can range from very small to very large. They can be quite deep, or they can be only moderately so. Ponds are frequently used as a synonym for lakes that have depths of less than six or seven feet and support plant life on the bottom.
The changing of the seasons can bring about significant fluctuations in temperature for the lakes that are found in certain temperate regions.
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What are 3 controllable and 3 uncontrollable risk factors?
Controllable risk factors are those that can be modified or changed through lifestyle choices or medical interventions. Uncontrollable risk factors are those that cannot be modified or changed.
Smoking is a major risk factor for many diseases, including lung cancer, heart disease, and stroke. Quitting smoking Controllable can significantly reduce the risk of these diseases. A diet high in saturated and trans fats, cholesterol, sodium, and added sugars Controllable can increase the risk of heart disease, risk factor stroke, and other chronic diseases. Eating a healthy diet that is rich in fruits, vegetables, whole grains, lean proteins, and healthy fats risk factor can lower the risk of these diseases. A Uncontrollable person's risk of certain diseases, such as heart disease and cancer, Uncontrollable risk factor can be influenced by their family history. Men have a higher risk of heart disease than women, while Uncontrollable risk factor women have a higher risk of osteoporosis and breast cancer.
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PLEASEEEEEEE HELP GUYS THIS MY FIRST BTOLOGY CLASS!! 2
The equation of line when a line passes through a point (-2, 7) and have slope 5, is y = 5x + 17> The blank words are slope, point, b in order.
What is a slope?In mathematics, a line's slope, also known as its gradient, is a numerical representation of the line's steepness and direction
Given:
Slope m = 5
And point (-2, 7)
Slope-intercept form: y = mx + b
If a line passes through a point (x₁ ,y₁) and have slope m
then the equation of line is
y - y₁ = m (x - x₁)
Substituting the values,
y - 7 = 5(x + 2)
Simplifying,
y = 5x + 17
Therefore, the equation is y = 5x + 17.
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humans the allele for normal blood clotting, B is dominant to the allele for hemophilia, b. This is a sex-linked trait und on the X chromosome. The last Tsar of Russia (Nicholas II did not have hemophilia. His wife (Alexandra) also did not have hemophilia. They had a hemophiline son, and four normal daughters. What is/are the probable genotype(s) for each member of the family? Tsar Nicholas Empress Alexandra Daughter Olga Nikolaevna Daughter Tatiana Nikolaevna Daughter Maria Nikolaevna Daughter Anastasia Nikolaevna Son Alexei Nikolaevich
Tsar Nicholas: XBXB (since he does not have hemophilia, he must be homozygous dominant for the normal blood clotting allele)
Empress Alexandra: XBXb (since she does not have hemophilia, she must be a carrier of the hemophilia allele)
Daughter Olga Nikolaevna: XBXB or XBXb (she could have inherited the normal allele from her father or the carrier allele from her mother)
Daughter Tatiana Nikolaevna: XBXB or XBXb (same as Olga)
Daughter Maria Nikolaevna: XBXB or XBXb (same as Olga)
Daughter Anastasia Nikolaevna: XBXB or XBXb (same as Olga)
Son Alexei Nikolaevich: XbXb (since he has hemophilia, he must have inherited the hemophilia allele from his mother and a second copy from his father, who is the carrier).
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Protons and neutrons each have a mass of (blank) amu
(Middle school science)
The nucleus accounts for almost the entire mass of the atom of any element, which means that a single proton or neutron has an approximate mass of 1 AMU.
What is AMU?
An atomic mass unit is defined as accurately 1/12 the mass of carbon-12 atom. carbon-12 atom has six neutrons and six protons in its nucleus. It is represented as a.m.u or u (unified). It is unit of mass used to express atomic masses. 1 a.m.u is average of the proton rest mass and neutron rest mass.
Protons and neutrons both weigh about one atomic mass unit (amu). Isotopes of same element will have the same atomic number but different mass numbers.
Protons carry single positive charge that have mass of one approximately one atomic mass unit. The atomic number is equal to number of protons found in an atom.
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Where most ATP is created in mitochondria?
Most ATP is produced in the mitochondrial matrix, which is the fluid-filled space inside the inner membrane of the mitochondria.
The process of ATP production in the mitochondria is called cellular respiration. It starts with the breakdown of glucose and other molecules in the cytoplasm by the process of glycolysis, which generates a small amount of ATP. The majority of the ATP is generated in the Mitochondria during the process of oxidative phosphorylation, where the electrons from the breakdown of glucose are passed through a series of protein complexes in the inner mitochondrial membrane, which generates a proton gradient that drives the production of ATP via ATP synthase.
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What causes different illnesses and even premature death?
Smoking cigarettes and being exposed to secondhand tobacco smoke are leading causes of premature death.
death that occurs earlier than the typical death age for a population. The average death age is around 75 years old. The biggest causes of early death in the US are smoking cigarettes and being around people who smoke. They can make people more vulnerable to developing cancer, heart disease, stroke, lung disease, and a host of other illnesses. Injuries are another reason for early mortality.
Ischemic heart disease, which accounts for 16% of all fatalities worldwide, is the world's leading cause of mortality. This disease has shown the highest increase in deaths since 2000, with an increase of more than 2 million deaths to 8.9 million deaths in 2019. The second and third most common killers, stroke and chronic obstructive pulmonary disease, respectively account for 11% and 6% of all fatalities.
Lower respiratory infections remained to be the most fatal communicable disease worldwide, ranking as the fourth most common cause of death. However, there have been fewer fatalities; in 2019, it claimed 2.6 million lives, 460 000 fewer than it did in 2000.
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Production of chlorofluorocarbons (CFC) gas which is proposed to be banned in India, is used in which of the following domestic products?
A. Television
B. Refrigerator
C. Tube light
D. Cooking gas
Production of chlorofluorocarbons (CFC) gas which is proposed to be banned in India, is used in refrigerators.
The correct option is B
What are chlorofluorocarbons (CFCs)?Chlorofluorocarbons and hydrochlorofluorocarbons are formed as volatile derivatives of methane, ethane, and propane. They are fully or partially halogenated hydrocarbons that contain carbon, hydrogen, chlorine, and fluorine. Freon, a brand name owned by DuPont, is another frequent name for them.
They were used formerly as refrigerants in refrigerators. However, it was discovered that the ozone layer in Earth's atmosphere, which shields the planet from the sun's harmful UV rays, might be destroyed by chlorofluorocarbons (CFCs). CFCs were widely utilized as refrigerant gases and as propellants in aerosol sprays when the scientists published their findings in 1974.
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what is the characteristics of each plant group?
Answer:
Plant groups, also known as plant taxa, are classified based on shared characteristics. Some characteristics used to classify plants include the structure and arrangement of leaves, stems, and roots; the presence or absence of vascular tissue; the type of flowers or reproductive structures; and the number of cotyledons (seed leaves) present in the seed. Here are some examples of plant groups and some of their characteristics:
Ferns: Ferns are non-flowering plants that reproduce using spores. They have leafy fronds and root systems, but they do not have true stems, leaves, or flowers. Ferns are characterized by their vascular tissue, which helps transport water and nutrients throughout the plant.
Conifers: Conifers are a group of gymnosperms (non-flowering seed plants) that includes trees such as pines, spruces, and firs. Conifers are characterized by their needle-like leaves and their ability to produce seeds in cones. They also have vascular tissue to transport water and nutrients throughout the plant.
Angiosperms: Angiosperms are a group of flowering plants that produce seeds enclosed in fruit. They are the most diverse group of plants and include a wide variety of trees, shrubs, herbs, and other types of plants. Angiosperms are characterized by their flowers and the presence of cotyledons in their seeds.
Monocots: Monocots are a group of flowering plants that have one cotyledon in their seeds. They are characterized by their parallel-veined leaves, fibrous root systems, and the presence of vascular tissue. Monocots include plants such as lilies, grasses, and orchids.
Dicots: Dicots are a group of flowering plants that have two cotyledons in their seeds. They are characterized by their branching vascular tissue, net-veined leaves, and the presence of a taproot system. Dicots include plants such as roses, tomatoes, and oak trees.
Which of the following is a true statement regarding photoreceptors? Check all that apply a. Rods are responsible for night vision. b. Rods are associated with photopic vision. c. Cones are associated with color vision. d. There are more cones than rods e. Cones function in brighter light.
the following is a true statement regarding photoreceptors is Rods are responsible for night vision.
What are the two types of photoreceptors?Two types of photoreceptors reside in the retina: cones and rods. The cones are responsible for daytime vision, while the rods respond under dark conditions. The cones come in three varieties: L, M, and S types.
What do rod photoreceptors detect?Photoreceptors in the retina are classified into two groups, named after their physical morphologies. Rod cells are highly sensitive to light and function in nightvision, whereas cone cells are capable of detecting a wide spectrum of light photons and are responsible for colour vision.
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The true statement about photoreceptors is-"Rods are responsible for night vision".
What are the four photoreceptors present in the eyes?There are four photoreceptor types in the human retina- Short-wavelength cones (blue), medium-wavelength cones (green), long-wavelength cones (red) and rods.
What is the main function of photoreceptors?Photoreceptors are specialized neurons found in the retina that convert light into electrical signals that stimulate physiological processes. Signals from the photoreceptors are sent through the optic nerve to the brain for processing.
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Explain changes in osmotic pressure that occurs when cells are placed in solutions of differing concentrations. Can you describe what happens to cells in different solutions:
Osmotic pressure relies upon simplest on temperature and the difference in the concentration throughout the membrane.
The osmotic pressure of a solution is proportional to the molar concentration of the solute debris withinside the answer. As quickly because the solute molecules will increase the osmotic strain of answer boom. Osmotic strain is laid low with attention and temperature. Concentration of solute and temperature every have an effect on the quantity of strain created through the motion of water throughout a membrane. Higher concentrations and better temperatures boom osmotic pressure. If a cell is positioned in a hypertonic solution, water will depart the cell, and the cell will shrink. In an isotonic environment, there's no water movement, so there's no use withinside the length of the cell. When a cell is positioned in a hypotonic environment, water will input the cell, and the cell will swell.
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Please help with this!
Patrick and Patty's son Patterson, who is heterozygous for pink body color (Pp) like his parents, gets married and has kids with Petunia, who is homozygous recessive for yellow skin. What is the likelihood that their kid will have yellow skin like it's mother?
a. 25% chance of yellow skin
b. 50% chance of yellow skin
c. 75% chance of yellow skin
d. it is not possible for their offspring to have yellow skin because Patterson has the dominant trait
Answer:
b. 50% chance of yellow skin
Explanation:
The likelihood that their kid will have yellow skin depends on the genetic makeup of both Patterson and Petunia. Patterson has the genotype Pp, which means he has one dominant allele for pink body color and one recessive allele for yellow body color. Petunia, on the other hand, has the genotype pp, which means she is homozygous recessive for yellow body color.
When they have children, each parent will contribute one of their alleles to their offspring. The offspring will have a 50% chance of inheriting the recessive allele for yellow body color from Patterson and a 50% chance of inheriting the recessive allele for yellow body color from Petunia. Therefore, the likelihood that their kid will have yellow skin is 50%.
how do you know that these kittens come from the same litter?
These kittens come from the same litter because kittens from same litter can look different.
facts about Kittens -
Due to the possibility that kittens from the same litter may have different fathers, certain litters may contain half-brothers and half-sisters. This can occur when female cats have many matings with different males over a short period of time, resulting in multiple pregnancies and one litter.
Brothers are likely to have similar colors because male kittens always inherit their mom's fur color. The coats of female kittens, especially those with different dads, can differ from those of their sisters because they inherit a combination of their mother's and father's coloring.
Kittens will pick up a lot from their siblings throughout the first few months of life. You might notice kittens engaging in competitive play as they practice hunting and other activities with their littermates. Although it can occasionally appear a touch violent, as long as they are each pursuing and pouncing on the other in turn, it is a fantastic way for them to develop new abilities.
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Substance X was isolated in a urine sample, but it is too big to pass through the glomerular filtration membrane. How is this possible
It was secreted later in the distal tubule. Erythrocytes (red blood cells) should not be seen in urine since they cannot pass past the filtration barrier.
Their existence implies the presence of illness or infection. Leukocytes are immunological cells that should not be seen in urine.
The filtration membrane allows water and tiny solutes to flow through while blocking blood cells and big proteins. These substances persist in the bloodstream. The filtrate (the fluid that has gone through the membrane) flows farther into the nephron from the glomerular capsule.
Urine dipsticks use chemical analysis to give qualitative examination of several analytes in urine. Dipstick detects the presence of protein, glucose, blood, ketones, bilirubin, urobilinogen, nitrite, and leukocyte esterase using dry chemical procedures.
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How do the respiratory and circulatory systems work together essay?
To supply oxygen and remove carbon dioxide, the circulatory and respiratory system works together.
The respiratory system is what aids in breathing in oxygen and breathing out carbon dioxide. The circulatory system is the system that assists in supplying tissues with oxygen from the lungs and in removing carbon dioxide from the tissues by way of the lungs. In this way, both of these processes assist in the supply of oxygen and the removal of carbon dioxide as waste.
The blood that carries waste (CO₂) from the tissue via the heart will first carry the oxygen inhaled to the lungs, where it will be exchanged with the blood. The oxygen will then be sent to the heart, where it will be used to pump oxygen-rich blood to the tissues. Additionally, blood that has lost oxygen will transport waste from the tissue.
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Use the information in the articles and in the introduction text to explain how gene therapy increase the probability of changing the inheritance of desired traits in people
According to the information in the articles and in the introduction text, gene therapy increases the probability of changing the inheritance of desired traits in people by improving the likelihood of a desired trait appearing in the offspring.
What is gene therapy?Gene therapy is a branch of medicine that focuses on altering a cell's genetic makeup to have a therapeutic impact or to treat a disease by replacing or repairing damaged genetic material.
Gene therapy improves the likelihood of desirable traits and attempts to treat illness or strengthen your body's resistance to illness by replacing a damaged gene or adding a new gene.
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What was the main aim of Mendel's experiment?
The main aim of Mendel's experiment was to understand the principles of inheritance of genetic traits in pea plants.
He performed a series of controlled crossbreeding experiments, where he carefully selected and crossbred pea plants that exhibited specific traits, such as seed color (yellow or green) and seed shape (round or wrinkled). He then recorded the characteristics of the resulting offspring and compared them to the characteristics of the parent plants. Through these experiments, Mendel discovered that certain traits were inherited in a predictable pattern, and that these patterns could be explained by the presence of genes that controlled the inheritance of each trait. He also discovered that these factors could be dominant or recessive, and that the combination of these factors determined the phenotype (observable characteristics) of the organism. These discoveries formed the basis of Mendel's laws of inheritance, which are considered to be the foundation of the field of genetics.
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The chemical (ethyl mercaptan) added to the otherwise odourless LPG cooking gas for imparting a detectable smell to the gas is a compound of
A. bromine
B. fluorine
C. chlorine
D. sulphur
The chemical (ethyl mercaptan) added to the otherwise odourless LPG cooking gas for imparting a detectable smell to the gas is a compound of sulfur. The correct option is D.
What is LPG?Propane, propylene, butylene, isobutane, and n-butane are only a few of the volatile hydrocarbon gases found in liquefied petroleum gas, which is a fuel gas.
LPG is a fuel gas used in cars, cooking appliances, and heating appliances. LPG exists inside the cylinder as both a liquid and a vapour (gas).
In order to give the normally odourless LPG cooking gas a noticeable smell, a chemical called ethyl mercaptan is added that is a compound of sulfur.
Thus, the correct option is D.
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how the expansion of housing developments in southern California might limit coyote population in the area
Answer:
Explanation:
There are several ways in which the expansion of housing developments in southern California might limit coyote population in the area:
Habitat loss: As housing developments are built, natural habitats are often destroyed, which can limit the available space for coyotes and other wildlife.
Human-wildlife conflict: As housing developments bring more people into close proximity with coyotes, there is an increased likelihood of conflict between humans and coyotes. This can lead to coyotes being killed or removed from the area.
Fragmentation of habitat: The expansion of housing developments can also lead to the fragmentation of coyote habitat, making it more difficult for coyotes to move and interact with other members of their species.
Changes in prey availability: Housing developments can also alter the availability of prey for coyotes, which can impact their population size.
Overall, the expansion of housing developments in southern California can have a negative impact on coyote populations by limiting their habitat, increasing the likelihood of conflict with humans, and disrupting their natural behaviors and ecological relationships.
What if the bunnie i wa breeding had the genotype of WW and WWLL. How many generation would I need to wait to get a hort haired black bunny?
The generation that must be waited for the offspring of the short-haired black rabbit is the second generation with a probability of 6.25% or 1/16
WW white rabbit genotype, ww black rabbit genotype, LL long hair, ll short hair. If the genotype of a WWll rabbit is crossed with a wwLL then:
Parents: WWll >< wwwLL
Gametes: Wl><wL
Filial: WwLl
100% of their offspring will be white with long hair (WwLl)
If we cross two offspring to create a second generation (both WwLl), we get the following punnett squares:
Parents: WwLl >< WwLl
Gametes: WL, Wl, wL, w >< WL, Wl, wL, wl
Second Filial:
WWLL (white with long hair)
WWL (white with long hair)
WwLL (white with long hair)
Wwll (white with short hair)
WWL (white with long hair)
WWll (white with short hair)
Wwll (white with short hair)
Wwll (white with short hair)
WwLL (white with long hair)
WwLl (white with long hair)
wwLL (black with long hair)
wwLl (black with long hair)
WwLl (white with long hair)
Wwll (white with long hair)
wwlL (black with long hair)
wwll (black with short hair)
The phenotypic ratio of the second generation is 9 (white with long hair) : 3 white with short hair): 3 (black with long hair) : 1 (black with short hair)
The complete questions:
What if the bunnies I was breeding had the genotypes of WWll and wwLL. How many generations would I need to wait to get a short-haired black bunny? Use Punnett Squares to show why.
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What are the four reasons why Mendel choose garden pea for his experiment?
Mendel chose garden pea for his experiment because they have shorter life span, are bise-xual, self pollinating and have visible physical characteristics.
Mendel conducted a lot of experiments during his study in genetics. He considered garden pea ideal for his experiments for a number of reasons. The first reason being that garden pea has a short life span and because of this they are able to grow very quickly and are easy to maintain. The second reason is that they have visible physical characteristics which makes them easy to observe and study.
The other two reasons being that garden peas have bise-xual flowers and because of this, these garden peas are self-pollinating. They do not need another plant for pollination and can also easily cross pollinate.
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In Drosophila, the gene for eye color (A), wing shape (B), and body color (C) are all found on the same chromosome. The following crossover frequencies for these genes were determined by & trihybrid test-cross experiments. Determine the sequence of genes A, B, and C on a chromosome. There are two correct answers: Crossover Frequency 12% Genes A&B A&C B&C 18%
The correct sequence of the genes A, B and C found on the same chromosome can be : B A C or C A B.
Genes are the part of DNA sequences that code for a certain protein responsible for a particular trait. These genes are present upon the chromosomes. Each chromatid can contain multiple genes on it.
According to the question, the crossover frequency between genes B and C is 18 % hence they are the farthest (18% = 18 centi-Morgan). And the frequency between genes A & B and A & C is 12% and 6% respectively. Therefore the distance of B and C is the sum of the remaining two. This determines the sequence could be B A C or C A B.
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Why is a decrease in genetic diversity bad?
A decrease in genetic diversity bad because it increases the risk of extinction of a population through inbreeding depression.
This is a result of despair brought on by inbreeding paired with a lack of ability to adjust to change. New alleles can be introduced in these situations to save the population. For a population to adapt to changing circumstances, genetic diversity is essential.
Genetic drift is a result of sampling error because individuals are randomly chosen when a population is sampled. A random selection is one in which each member of the population has an equal chance of being chosen.
The variety of various inherited features within a species is referred to as genetic diversity. There would be many people with a wide range of diverse traits in a species with significant genetic diversity. For a population to adapt to changing surroundings, genetic variety is essential.
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In 3-5 sentences explain what mitosis does in fetal development. Include how the same DNA is in every cell, and how the fetus grows in size.
Mitosis is the process of cell division that occurs during fetal development, allowing the same DNA to be replicated in every cell.
Mitosis is a cell division process responsible for the growth and development of the fetus, as well as the formation of all the different types of cells that make up the body. During mitosis, the chromosomes in the nucleus of a cell are replicated and then separated into two identical sets, each of which goes into a separate daughter cell. This ensures that each new cell created during fetal development has the same genetic information or DNA as the original cell. As the number of cells increases, the fetus grows in size.
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Recreate the sequence that occurs in the carbon cycle beginning with carbon dioxide gas.
Our atmosphere also contains it as carbon dioxide, or CO2. Calcium, magnesium, potassium, or sodium ions are released as the acid dissolves the rocks, a process known as chemical weathering.
What carbon cycle beginning with carbon dioxide gas?As carbon dioxide, or CO2, it is also present in our atmosphere. Rain starts the transfer of carbon from the atmosphere to the rocks, or lithosphere. Rain is a result of the weak acid, carbonic acid, which is created when atmospheric carbon and water interact.
Therefore, When animals perish, volcanoes erupt, fires burn, fossil fuels are consumed, among other processes, carbon is released back into the atmosphere.
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How might a mutation affect the active site of an enzyme?
A mutation that occurs in a region of the DNA that codes for an amino acid sequence found in the active site of an enzyme can change the folded morphology of the active site and its affinity for its substrate.
Large regions of DNA can replicate when there is a mutation, usually as a result of genetic recombination. Animal genomes duplicate tens to hundreds of genes per million years, creating a significant genetic resource for the generation of new genes. The bulk of genes can be classified into bigger gene families that share an ancestor using sequence homology. The procedures that most typically result in novel genes are the duplication and mutation of an ancestral gene or the recombination of segments from several genes to create new combinations with novel functions. When connected, protein domains work as modules, each with a distinct purpose, to create genes that code for new proteins with unusual features.
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Use this sentence: A fault cuts across several layers of rock. Which conclusion can be made?
A. The fault is younger than the layers of rock based on the law of inclusion.
B. The fault is younger than the layers of rock based on the law of crosscutting. C. The fault is older than the layers of rock based on the law of inclusion.
D. The fault is older than the layers of rock based on the law of crosscutting.
Answer:
I think its B
Explanation:
I DK if I'm right bc I'm stuck on the same question
just get one wrong and if you get everything else right, it won't matter at all.
Many lethal genetic disorders such as CF, Huntington’s, sickle cell anemia, Tay Sach’s, etc., persist in the human genome.
How have these genes survived so many millennia of evolution (why didn’t they die out)?
These genes survived so many millennia of evolution because most of the genetic disorders are caused due to mutation in genome.
What is Mutation?This is referred to as an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA by different factors.
The factors which cause mutation in individuals are exposure to mutagens or a viral infection which may be due to the high increase in the technology available in the environment in which they live and operate
These genes such as those which cause disorders such as Huntington’s, sickle cell anemia, Tay Sach’s, etc survived so many millennia of evolution because there is still the cause being present in our everyday world which is therefore the reason why it was chosen as the correct choice.
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A team of biologists discovers a new ecosystem with a large lake and lush vegetation surrounding it. They monitor the ecosystem for a year but record no rainfall during that time. Which statement best explains the state of the water cycle in this ecosystem? The water is gathered in lakes or flows to oceans. The water in the atmosphere forms dew, fog, or clouds. Water stays predominantly in lakes or groundwater sources. Water is frozen underground instead of flowing on the surface.
The statement that best explains the state of the water cycle in this ecosystem is: Water stays predominantly in lakes or groundwater sources.
The correct option is C.
What is an ecosystem?The entire group of organisms and the natural setting in which they live together make up an ecosystem. Through nutrient cycles and energy exchanges, these biotic and abiotic elements are interconnected. Photosynthesis is the mechanism by which energy enters the system and is absorbed into plant tissue.
Since no rainfall occurs during the year of study in the ecosystem, the water is present in lakes and underground water.
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